Why is the incidence of sickle-cell anemia an excellent example of a “balanced polymorphism,” in which two or more alleles are maintained by natural selection in a population?

Please provide detailed answers for the following questions:

A. In your own words describe each of the four forces of evolution, what you understand from them.

B. Why is the incidence of sickle-cell anemia an excellent example of a “balanced polymorphism,” in which two or more alleles are maintained by natural selection in a population?

C. Why is a frameshift mutation far more likely to lead to a defective protein compared with a point mutation?

D. Explain how the founders effect can lead to a descendant population that differs greatly from its parent population over a relatively short period of time?

 
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